If you’ve had a bone marrow transplant, you may have some questions about the impact of cytomegalovirus (CMV)

What does CMV have to do with a bone marrow transplant?

A healthy immune system can keep CMV from causing sickness. However, if the immune system is weakened, CMV can cause sickness.

Some of the medicines that are needed for a bone marrow transplant can weaken the immune system. These include medicines that keep the body from rejecting a transplant. During this time, CMV may cause sickness.

Before a bone marrow transplant, people are tested for CMV. Laboratory tests, such as blood tests, can detect CMV. With testing, healthcare providers know who has a greater risk for sickness from CMV. CMV testing continues after a bone marrow transplant. The testing helps healthcare providers monitor CMV to determine if the virus is growing or multiplying.

How can CMV impact a bone marrow transplant?

CMV may become active after a bone marrow transplant and cause problems that can affect recovery. For example, sickness from CMV can affect the lungs, stomach, eyes, and liver.

Learn about PREVYMIS

About PREVYMIS

Learn about CMV

Understanding CMV

What is PREVYMIS® (letermovir)?

PREVYMIS is a prescription medicine used to help prevent:

  • Cytomegalovirus (CMV) infection and disease in adults who have received an allogeneic hematopoietic stem cell (bone marrow) transplant and have a high risk for getting CMV infection and disease.
  • CMV disease in adults who have received a kidney transplant and have a high risk for getting CMV disease.

Important Safety Information

Do not take PREVYMIS if you take pimozide or ergot alkaloids.

 

If you are taking PREVYMIS with cyclosporine, do not take pitavastatin or simvastatin.

 

Before taking PREVYMIS, tell your healthcare provider about all your medical conditions, including if you have kidney or liver problems; are pregnant or plan to become pregnant, since it is not known if PREVYMIS will harm your unborn baby; and if you are breastfeeding or plan to breastfeed, since it is not known if PREVYMIS passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby while taking PREVYMIS.

 

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. PREVYMIS may affect the way other medicines work, and other medicines may affect how PREVYMIS works and can cause serious side effects.

 

Know the medicines you take. Keep a list of medicines and show it to your healthcare provider and pharmacist when you get a new medicine. Your healthcare provider or pharmacist will tell you if it is safe to take PREVYMIS with other medicines. Do not start or stop taking another medicine without telling your healthcare provider first.

 

The most common side effects of PREVYMIS in adults who have received a hematopoietic stem cell transplant include: nausea, diarrhea, vomiting, swelling in your arms and legs, cough, headache, tiredness, and stomach (abdominal) pain.

 

The most common side effect of PREVYMIS in adults who have received a kidney transplant is diarrhea.

 

These are not all the possible side effects of PREVYMIS.

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

 

Please read the accompanying Patient Information and Instructions for Use for PREVYMIS, and discuss them with your doctor.
The Physician Prescribing Information also is available.

What is PREVYMIS® (letermovir)?

PREVYMIS is a prescription medicine used to help prevent:

  • Cytomegalovirus (CMV) infection and disease in adults who have received an allogeneic hematopoietic stem cell (bone marrow) transplant and have a high risk for getting CMV infection and disease.
  • CMV disease in adults who have received a kidney transplant and have a high risk for getting CMV disease.

PREVYMIS is a prescription medicine used to help prevent:

  • Cytomegalovirus (CMV) infection and disease in adults who have received an allogeneic

PREVYMIS is a prescription medicine used to help prevent:

  • Cytomegalovirus (CMV) infection and disease in adults who have received an allogeneic hematopoietic stem cell (bone marrow) transplant and have a high risk for getting CMV infection and disease.
  • CMV disease in adults who have received a kidney transplant and have a high risk for getting CMV disease.

Important Safety Information About PREVYMIS® (letermovir)

Do not take PREVYMIS if you take pimozide or ergot alkaloids.

 

If you are taking PREVYMIS with cyclosporine, do not take pitavastatin or simvastatin.

 

Before taking PREVYMIS, tell your healthcare provider about all your medical conditions, including if you have kidney or liver problems; are pregnant or plan to become pregnant, since it is not known if PREVYMIS will harm your unborn baby; and if you are breastfeeding or plan to breastfeed, since it is not known if PREVYMIS passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby while taking PREVYMIS.

 

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. PREVYMIS may affect the way other medicines work, and other medicines may affect how PREVYMIS works and can cause serious side effects.

 

Know the medicines you take. Keep a list of medicines and show it to your healthcare provider and pharmacist when you get a new medicine. Your healthcare provider or pharmacist will tell you if it is safe to take PREVYMIS with other medicines. Do not start or stop taking another medicine without telling your healthcare provider first.

 

The most common side effects of PREVYMIS in adults who have received a hematopoietic stem cell transplant include: nausea, diarrhea, vomiting, swelling in your arms and legs, cough, headache, tiredness, and stomach (abdominal) pain.

 

The most common side effect of PREVYMIS in adults who have received a kidney transplant is diarrhea.

 

These are not all the possible side effects of PREVYMIS.

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

 

Please read the accompanying Patient Information and Instructions for Use for PREVYMIS, and discuss them with your doctor.
The Physician Prescribing Information also is available.

Do not take PREVYMIS if you take pimozide or ergot alkaloids.

Do not take PREVYMIS if you take pimozide or ergot alkaloids.

If you are taking PREVYMIS with cyclosporine, do not take pitavastatin or simvastatin.

Before taking PREVYMIS, tell your healthcare provider about all your medical conditions, including if you have kidney or liver problems; are pregnant or plan